It appears that Sam Rockwell and Mickey Rourke are up for the roles of villains in Iron Man 2. It appears the villains for this film will be Whiplash (possibly Rourke) and Justin Hammer (possibly Rockwell).
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According to the article, Terrence Howard has been replaced by Don Cheadle in the role of James Rhodes. I liked Howard, but I personally think this will be an improvement.
In case you're wondering what the villains in question look like...
Whiplash
Justin Hammer